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Celebrex vs Meloxicam: Understanding the Differences for Arthritis Relief

celebrex vs meloxicam

Arthritis can make daily activities challenging due to joint pain and inflammation. Celebrex and Meloxicam are two medications commonly prescribed to manage arthritis symptoms. Find out how Celebrex and Meloxicam are different so you can decide which one might work best for you.

Understanding Celebrex and Meloxicam

Celebrex, also known as Celecoxib, is a type of medication that helps reduce inflammation and pain. It works by specifically targeting the hormones in the body that generate these symptoms. Celebrex is often given to people with osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It can help with severe pain and cramps during your period.

On the other hand, Meloxicam, sold under the brand name Mobic, is another medication that belongs to the same group of drugs as Celebrex. Meloxicam is the same as Celebrex; it both reduces inflammation and pain. Meloxicam works by inhibiting the formation of molecules in the body known as prostaglandins, which play a role in the inflammatory response.

Meloxicam vs. Celebrex: The Differences

Celebrex and Meloxicam are both drugs that help with pain and inflammation, but they work a bit differently:

How They Work

  • Celebrex mainly targets one enzyme to reduce inflammation.
  • Meloxicam targets two enzymes, which can cause more stomach issues.


  • Both drugs are good for arthritis pain, but Celebrex might be gentler on the stomach.

How to Take

  • Celebrex is often given once or twice per day, with or without food.
  • Once a day, with or without food, you can take meloxicam.


  • Celebrex is often more expensive than Meloxicam because it’s a brand-name drug.

In short, Celebrex might be better if you’re worried about stomach problems, but Meloxicam could be a more affordable choice.

Meloxicam or Celebrex: Which is better for arthritis?

Celebrex (Celecoxib) and Meloxicam are both used to treat pain and swelling, but they’re often used for different reasons:

  • Celebrex: It’s mainly used for arthritis, like osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It can also relieve short-term discomfort and menstrual cramps. Celebrex might be a better choice if you’re worried about stomach problems.
  • Meloxicam: This one also helps with arthritis pain, including osteoarthritis and rheumatoid arthritis. But, Celebrex is better than Meloxicam, as it makes you more likely to upset your stomach. It can also help with short-term pain and swelling.

Side Effects of Meloxicam and Celebrex

Meloxicam and Celebrex can both cause side effects, but they may be different for different people. Here are some common side effects:


  • Upset stomach, like indigestion, heartburn, or stomach pain
  • When your bowel movements change, like when you have diarrhea or constipation
  • Feeling sick or throwing up
  • Feeling dizzy or having headaches
  • Swelling in the legs or feet
  • High blood pressure


  • Stomach issues, such as pain, indigestion, or heartburn
  • Changing bowel movements, like having diarrhea or constipation
  • Gas
  • Swelling in the hands, feet, ankles, or legs
  • Feeling dizzy or having headaches
  • Upper respiratory tract infection

Both drugs can also increase the risk of serious heart problems, especially if used for a long time or in high doses. They can also cause stomach ulcers or bleeding, which can be dangerous. Talk to your doctor if you have any side effects. They can help you decide if you need to adjust your treatment.

Warnings & Precautions when using Celebrex and Meloxicam

When using Celebrex (Celecoxib) or Meloxicam, there are some important warnings and precautions to keep in mind:

  • Cardiovascular Risk: Both medications can increase the risk of serious cardiovascular events such as heart attack or stroke, especially in people with existing heart conditions or risk factors. It is essential to use the smallest amount that works for as little time as possible, especially if you are going to be using it for a long time.
  • Gastrointestinal Risk: NSAIDs such as Celebrex and Meloxicam can raise the risk of stomach ulcers, bleeding, and other digestive problems. Taking these drugs with food or a stomach protector can help lower the risk.
  • Renal Toxicity: Both medications can impair kidney function, particularly in patients with pre-existing kidney illnesses. It’s important to monitor kidney function regularly when using these medications.
  • Allergic Reactions: Certain people may have severe allergic reactions to Celebrex or Meloxicam. A rash, burning, swelling, feeling lost, and having trouble breathing are some of the symptoms. If you have these signs, you should see a doctor right away.
  • Drug Interactions: Both drugs might not work well with other prescription drugs like blood thinners, ACE inhibitors, and diuretics. Tell your doctor or nurse about all the medicines you are taking so that they can avoid possible problems.
  • Pregnancy and breastfeeding: Celebrex and Meloxicam should be avoided throughout the third trimester of pregnancy since they may affect the developing infant. Also, you shouldn’t eat them while nursing because they can get into the milk.
  • Other Precautions: People with a history of stomach ulcers, liver or kidney disease, heart disease, or high blood pressure should use these medications with caution and under the supervision of a healthcare provider.

Celebrex vs. Meloxicam: Effective Usage is the Key!

Meloxicam and Celebrex (Celecoxib) are two medicines that are used to treat pain and swelling, like arthritis. Celebrex might be better if you’re worried about stomach issues, while Meloxicam is more likely to upset your stomach. However, both drugs can increase the risk of serious heart problems and should be used carefully, especially if you have heart issues. It’s important to talk to your doctor to figure out which medication is best for you based on your health needs.


  • Diane Silva

    Diane is a travel enthusiast, content creator, and master storyteller, capturing her adventures through captivating blogs and engaging vlogs. With a passion for the great outdoors and a love for literature, she brings a unique perspective to the travel world. Whether she's exploring hidden gems or discussing the latest trends, Diane is your go-to source for all things travel and beyond.